Endocrine Abstracts

Diabetes mellitus (DM) type MODY (Maturity Onset Diabetes of the Young) accounts 10% of cases of diabetes with onset before 35 years. The aim was to determine characteristics of the course of the main types of MODY.Materials and Methods: 45 patients aged 18 to 35 years diagnosed with MODY molecular genetic testing (next-generation sequencing technology and direct automated Sanger sequencing) were included: 31 had mutations in the GCK gene, 14 - ...

The age group under 45 years is the most difficult to determine the type of diabetes mellitus (DM), it can include type 1 (DM1), type 2 (DM2), MODY and LADA diabetes. Objective of the study: to determine clinical markers for differential diagnosis of types of DM in young patients.Materials and Methods: 202 patients with onset of diabetes aged 18 to 45 years were included: group 1 - 77 patients with MODY, 2 - 83 with DM 2, 3 - 14 with DM 1, 4 - 28 with LA...